During a stopover in Germany in the middle of a carefree road trip through Europe, two American girls find themselves alone at night when their car breaks down in the woods. Searching for help at a nearby villa, they are wooed into the clutches of a deranged retired surgeon who explains his mad scientific vision to his captives' utter horror. They are to be the subjects of his sick lifetime fantasy: to be the first to connect people, one to the next, and in doing so bring to life "the human centipede."
Unfortunately the movie The Human Centipede (First Sequence) is not yet available on Disney Plus.
| Directing | Tom Six | Director |
| Writing | Tom Six | Writer |
| Production | Tom Six | Producer |
| Camera | Goof de Koning | Director of Photography |
| Sound | Patrick Savage | Music |
| Sound | Holeg Spies | Music |
| Editing | Nigel de Hond | Editor |
| Art | Stefan Thomas | Production Design |
| Art | Stefan Johannes | Art Direction |
| Art | Caroline Lucciari | Set Decoration |
| Costume & Make-Up | Rachel Elbertse | Makeup Department Head |
| Production | Yumi Takada | Casting |
| Sound | Sefi Carmel | Sound Re-Recording Mixer |
| Sound | Eilam Hoffman | Supervising Sound Editor |
| Sound | Tomer Kantor | Sound Editor |
| Sound | Tomer Kantor | Sound Effects Editor |
| Sound | Ariel Levinsohn | Sound Effects Editor |
| Sound | Andrew Lewis | Sound Editor |
