Sequel/spin-off of the gag manga classic Osomatsu-kun, entailing the lives of the now 20-something NEET virgin Matsuno sextuplets and the bizarre adventures they find themselves into in the modern day.
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| Title | Air Date | Duration | ||
|---|---|---|---|---|
| Season 1 | Episode 1 | Osomatsu-kun Returns | 2015-10-06 | 23 min |
| Season 1 | Episode 2 | Let's Get a Job / The Melancholy of Osomatsu | 2015-10-13 | 23 min |
| Season 1 | Episode 3 | Tidbits Collection | 2015-10-20 | 23 min |
| Season 1 | Episode 4 | Let's Become Independent / This is Totoko | 2015-10-27 | 23 min |
| Season 1 | Episode 5 | The Karamatsu Incident / ESP Kitty | 2015-11-03 | 23 min |
| Season 1 | Episode 6 | It's a Birthday Party, Dajo / Iyami's Great Discovery | 2015-11-10 | 23 min |
| Season 1 | Episode 7 | Todomatsu and the Five Demons / Four / Going North | 2015-11-17 | 23 min |
| Season 1 | Episode 8 | The Calming Osomatsu / Totoko's Dream | 2015-11-24 | 23 min |
| Season 1 | Episode 9 | Chibita and Oden / Jyushimatsu Falls in Love | 2015-12-01 | 23 min |
| Season 1 | Episode 10 | Iyami and Chibita's Rental Girlfriend | 2015-12-08 | 23 min |
| Season 1 | Episode 11 | Black Santa / Picked Up by a Girl / The Perfect Christmas / Exchanging Presents / Christmas Drinking / Groveling | 2015-12-15 | 23 min |
| Season 1 | Episode 12 | Year-End Special-san | 2015-12-22 | 23 min |
| Season 1 | Episode 13 | Sanematsu-san / Girlymatsu-san / Accident? | 2016-01-05 | 23 min |
| Season 1 | Episode 14 | We Caught a Cold / Todomatsu's Line / Choromatsu-sensei | 2016-01-12 | 23 min |
| Season 1 | Episode 15 | Interview / The Life of Chibita's Flower | 2016-01-19 | 23 min |
| Season 1 | Episode 16 | Matsuno Matsunan / The Ichimatsu Incident | 2016-01-26 | 23 min |
| Season 1 | Episode 17 | Jyushimatsu Festival | 2016-02-02 | 23 min |
| Season 1 | Episode 18 | Girlymatsu-san / Iyami`s Counterattack | 2016-02-09 | 23 min |
| Season 1 | Episode 19 | Hijirisawa Shonosuke-san | 2016-02-16 | 23 min |
| Season 1 | Episode 20 | Teach Me, Hatabou / School Master / Iyami's School | 2016-02-23 | 23 min |
| Season 1 | Episode 21 | Mahjong / God Matsu | 2016-03-01 | 23 min |
| Season 1 | Episode 22 | The Star of Hope, Todomatsu / Final Sheeeh | 2016-03-08 | 23 min |
| Season 1 | Episode 23 | Kerosene / Dayon Tribe | 2016-03-15 | 23 min |
| Season 1 | Episode 24 | Totoko's Huge Panic / Letter | 2016-03-22 | 23 min |
| Season 1 | Episode 25 | Osomatsu-san, Such as It Was | 2016-03-29 | 23 min |
| Season 2 | Episode 1 | Mr. Osomatsu Returns | 2017-10-02 | 23 min |
| Season 2 | Episode 2 | Congratulations! Employment!! / Super Detergent | 2017-10-09 | 23 min |
| Season 2 | Episode 3 | Totoko's Challenge | 2017-10-16 | 23 min |
| Season 2 | Episode 4 | Matsuzou and Matsuyo | 2017-10-23 | 23 min |
| Season 2 | Episode 5 | Osomatsu-san in the Summer | 2017-10-30 | 23 min |
| Season 2 | Episode 6 | Iyami Has Arrived | 2017-11-06 | 23 min |
| Season 2 | Episode 7 | Osomatsu and Todomatsu | 2017-11-13 | 23 min |
| Season 2 | Episode 8 | Jyushimatsu and the Dolphin / Totoko and Nyaa | 2017-11-20 | 23 min |
| Season 2 | Episode 9 | Campaign Starting Now! | 2017-11-27 | 23 min |
| Season 2 | Episode 10 | Karamatsu and Brother | 2017-12-04 | 23 min |
| Season 2 | Episode 11 | Chibita's Revenge | 2017-12-11 | 23 min |
| Season 2 | Episode 12 | The Eitaro Family | 2017-12-18 | 23 min |
| Season 2 | Episode 13 | End of the Year | 2017-12-25 | 23 min |
| Season 2 | Episode 14 | The Choromatsu Incident | 2018-01-08 | 23 min |
| Season 2 | Episode 15 | Jar / Karamatsu Taxi / Totty Quiz | 2018-01-15 | 23 min |
| Season 2 | Episode 16 | Space Pirates / Gourmet Round / The Cutie Next Door | 2018-01-22 | 23 min |
| Season 2 | Episode 17 | Punishment / Inn | 2018-01-29 | 23 min |
| Season 2 | Episode 18 | Iyami, Alone in the Wind | 2018-02-05 | 23 min |
| Season 2 | Episode 19 | Ventriloquism / Valentine's Day | 2018-02-12 | 23 min |
| Season 2 | Episode 20 | Tidbits Collection 2 | 2018-02-19 | 23 min |
| Season 2 | Episode 21 | The Late Night Himatsuya / BANANA / NEET Correctional Facility | 2018-02-26 | 23 min |
| Season 2 | Episode 22 | Overseas Vacation | 2018-03-05 | 23 min |
| Season 2 | Episode 23 | The Late Night Himatsuya / Dayon and Dayon / Iyami-san is Troubled | 2018-03-12 | 23 min |
| Season 2 | Episode 24 | Cherry Blossoms | 2018-03-19 | 23 min |
| Season 2 | Episode 25 | Mr. Osomatsu in Hell | 2018-03-26 | 23 min |
| Season 3 | Episode 1 | Untitled | 2020-10-12 | 23 min |
| Season 3 | Episode 2 | Delivery | 2020-10-19 | 23 min |
| Season 3 | Episode 3 | Estimated Value | 2020-10-26 | 23 min |
| Season 3 | Episode 4 | Unit Formed | 2020-11-02 | 23 min |
| Season 3 | Episode 5 | The Way Home | 2020-11-09 | 23 min |
| Season 3 | Episode 6 | Touter / Optimization / Massage | 2020-11-16 | 23 min |
| Season 3 | Episode 7 | Tidbits Collection 3 | 2020-11-23 | 23 min |
| Season 3 | Episode 8 | To the South | 2020-11-30 | 23 min |
| Season 3 | Episode 9 | Let's Do Chores | 2020-12-07 | 23 min |
| Season 3 | Episode 10 | Werewolf | 2020-12-21 | 23 min |
| Season 3 | Episode 11 | Pizza | 2020-12-28 | 23 min |
| Season 3 | Episode 12 | AI | 2020-12-28 | 23 min |
| Season 3 | Episode 13 | Mr. HNYmatsu | 2021-01-04 | 23 min |
| Season 3 | Episode 14 | Sparkle Phantom Stream | 2021-01-11 | 23 min |
| Season 3 | Episode 15 | Cosplaymatsu | 2021-01-18 | 23 min |
| Season 3 | Episode 16 | SaneCop / Nanmaider Attacks | 2021-01-25 | 23 min |
| Season 3 | Episode 17 | The Riceballs' New Routine / Imoni | 2021-02-01 | 23 min |
| Season 3 | Episode 18 | Just Don't | 2021-02-08 | 23 min |
| Season 3 | Episode 19 | Are They Disbanding? / Sumo Stable / Dogs | 2021-02-15 | 23 min |
| Season 3 | Episode 20 | Let's Buy Them / Choromatsu Memorial Hall / Ear Cleaning / Persimmons | 2021-02-22 | 23 min |
| Season 3 | Episode 21 | Is That Okay? / Greenroom / Totoderella | 2021-03-01 | 23 min |
| Season 3 | Episode 22 | I Found This / Wannabe Detectives / Hide-and-Seek | 2021-03-08 | 23 min |
| Season 3 | Episode 23 | Contract Renewals / Shopping / Friends / If Doubts | 2021-03-15 | 23 min |
| Season 3 | Episode 24 | New Osomatsu Returns / A-1 Grand Prix | 2021-03-22 | 23 min |
| Season 3 | Episode 25 | Bored | 2021-03-29 | 23 min |
| Season 4 | Episode 1 | It's Starting Again | 2025-07-08 | 23 min |
| Season 4 | Episode 2 | Watermelon Alien | 2025-07-15 | 23 min |
| Season 4 | Episode 3 | Thunderstorms and Crew Cuts | 2025-07-22 | 23 min |
| Season 4 | Episode 4 | Temple Festival | 2025-07-29 | 23 min |
| Season 4 | Episode 5 | Rest | Fishing Hermit | 2025-08-05 | 23 min |
| Season 4 | Episode 6 | Fans and Time Machines | 2025-08-12 | 23 min |
| Season 4 | Episode 7 | Storytime, Jo | 2025-08-19 | 23 min |
| Season 4 | Episode 8 | Ichimatsu and the Thieving Cat | 2025-08-26 | 23 min |
| Season 4 | Episode 9 | The Idiot Series | 2025-09-02 | 23 min |
| Season 4 | Episode 10 | Iyami and the Hikikomijian Alien | 2025-09-09 | 23 min |
| Season 4 | Episode 11 | The Sextuplets Have the Same Dream | 2025-09-16 | 23 min |
| Season 4 | Episode 12 | The End of Summer | 2025-09-23 | 23 min |
| Season 4 | Episode 13 | Episode 13 | 23 min |
| Sound | Issa Hentona | Theme Song Performance |
| Writing | Shu Matsubara | Series Composition |
| Visual Effects | Kumiko Numata | Character Designer |
| Visual Effects | Naoyuki Asano | Character Designer |
| Visual Effects | Yukiko Kakita | Color Designer |
| Sound | AOP | Theme Song Performance |
| Writing | Fujio Akatsuka | Original Series Creator |
