After healing the leg of the murderer John Wilkes Booth, responsible for the assassination of President Abraham Lincoln, perpetrated on April 14, 1865, during a performance at Ford's Theatre in Washington; Dr. Samuel A. Mudd, considered part of the atrocious conspiracy, is sentenced to life imprisonment and sent to the sinister Shark Island Prison.
Unfortunately the movie The Prisoner of Shark Island is not yet available on Disney Plus.
| Sound | W.D. Flick | Sound |
| Sound | Roger Heman Sr. | Sound |
| Costume & Make-Up | Gwen Wakeling | Costume Designer |
| Sound | Louis Silvers | Music Director |
| Crew | Joseph M. Schenck | Presenter |
| Directing | John Ford | Director |
| Writing | Nunnally Johnson | Screenplay |
| Editing | Jack Murray | Editor |
| Art | Thomas Little | Set Decoration |
| Production | Darryl F. Zanuck | Producer |
| Art | William S. Darling | Art Direction |
| Production | Nunnally Johnson | Associate Producer |
| Directing | Edward O'Fearna | Assistant Director |
| Camera | Bert Glennon | Director of Photography |
| Sound | R. H. Bassett | Original Music Composer |
| Sound | Hugo Friedhofer | Original Music Composer |
| Crew | Tom Steele | Stunts |